Platelets are tiny cells that are present in the blood and help the body in the formation of blood clots and prevention of continuous and profuse bleeding. If one of the blood vessels are damaged, platelets are activated, which then reach the site of damage and repair it by producing a platelet plug.
The process of spread of platelets across the surface of the damaged blood vessels is called adhesion. When platelets arrive at the damage site, they adhere to one another and also send out signals to attract more platelets. This process is referred to as aggregation. Platelets play a very important role in the process of stoppage of bleeding.
Normally, there are around 150,000 to 400,000 platelets in one microlitre of blood. If an individual’s platelet count is less than 1,50,000, they are said to be thrombocytopenic. On the other hand, if someone has a platelet count above 400,000, the condition is called thrombocytosis. The platelet count is determined with the help of a routine blood test called complete blood count (CBC). Many diseases are associated with a reduced platelet count. All these conditions are linked with failure to form clots which manifests as continuous bleeding. These patients, therefore, require platelet transfusions.
Below are certain medical conditions linked with abnormal platelets or abnormal platelet counts:
Certain factors are responsible for causing thrombocytopenia including liver disease, medications, pregnancy, infections, and abnormal immune system. Following are some signs and symptoms of thrombocytopenia:
If you experience signs and symptoms of thrombocytopenia that are worrisome, you must seek help from a healthcare provider. If the bleeding does not cease to stop or if it does not respond to first-aid techniques, seek immediate medical help and attention.
Platelets are generated in the bone marrow. Certain factors are responsible for a reduction in platelet production, including:
Some medical conditions make the body damage platelets or use those up faster than they are generated. Due to this, a shortage of platelets occurs in the bloodstream. Following are examples of such conditions:
When there is a fall in platelet count below 10,000 platelets per microlitre, life-threatening internal bleeding may occur. Even though it is uncommon, severe types of thrombocytopenia can lead to life-threatening bleeding in the brain.
Below are some eligibility criteria for Single Donor platelet donation:
Below are some eligibility criteria for blood donations:
A haemoglobin screening is performed on platelet donors just like for a blood donor. A confidential medical history is collected and a physical examination is done to check the donor’s vital parameters including pulse rate, blood pressure, temperature, and haemoglobin level. Blood samples are taken from the donor and forwarded to the laboratory for certain investigations including malaria screening, triple serology, and complete blood count. The results are valid for only 7 days to 1 month after the sample is collected. If platelet donation occurs after one month, the donors are tested again for the above parameters.
Some facts a platelet donor should know:
The plateletpheresis procedure has an immediate and powerful impact on the life of a cancer patient. The platelets are transfused to a patient within a week and they could play a major role in keeping them alive. Platelets are mostly used for cancer patients, but also help patients with undergoing open-heart surgery and organ transplants or blood disorders. Because platelets need to be transfused within a week of collection, platelet donors are constantly needed to keep the supply stable.
Does your loved one need a platelet transfusion in Indore? Are you a platelet donor? If you are looking for a centre for plateletpheresis in Indore, you can visit the Blood Centre and Transfusion Medicine Department at Kokilaben Dhirubhai Ambani Hospital, Indore and seek help. Our department is equipped with state-of-the-art infrastructure and advanced medical instruments. Our staff members are highly qualified and experienced and deliver all services with utmost care and professionalism. International protocols and quality standards are followed during all the procedures.