The Biochemistry Laboratory at Kokilaben Dhirubhai Ambani Hospital, Indore offers a diverse range of biochemical investigations of the body fluids such as urine, blood, and cerebrospinal fluid. The laboratory provides both routine and specialised testing in areas like immunology, tumour markers, vitamins, and therapeutic drug monitoring. The testing is performed by a team of highly skilled technical laboratory personnel who work under the supervision of an experienced and certified medical biochemist.
The team is responsible for the appropriate interpretation of results and use of investigations. It aims to provide cost-effective, excellent, evidence-based patient care in a clinically relevant turnaround time. Our Biochemistry Laboratory has the latest state-of-the-art equipment with complete backups and we offer 24 x 7 round-the-clock services. Our commitment to quality improvement combined with extensive training helps us deliver the best possible services in the tertiary care hospital settings.
Metabolism is the chemical processes that happens in the body and the body requires these processes to sustain life. Inherited metabolic disorders happen when abnormal chemical reactions interfere with these processes.
Some inherited disorders of metabolism can be diagnosed before birth or at the time of birth during a routine physical examination. The symptoms may also appear later.
Inherited metabolic disorders are uncommon genetic conditions that make the metabolism of a person to not function properly. Metabolism is an important chemical process through which food is converted into energy and toxins are removed from the body. Genetic defects pass down from parents to children and they cause abnormal chemical reactions that interfere with metabolism.
These disorders affect the ability of the body to convert food into energy and remove unhealthy substances and waste products. Cell development and brain function can be damaged due to some conditions. Inherited metabolic disorders are also referred to as inborn errors of metabolism and hereditary metabolic disorders.
Following are some common inherited metabolic disorders:
Genetic defects passed from generation to generation cause inherited metabolic disorders. Genetic changes can lead to a deficiency in enzymes or hormones. These deficiencies lead to abnormal chemical reactions that prevent the metabolism from working properly.
The symptoms of inherited metabolic disorders differ, depending on the condition. While the symptoms are sometimes mild, at other times are debilitating. Some symptoms include weight loss, developmental delay, seizures, growth disorder, poor appetite and energy levels, abdominal pain, and unusual odours in sweat, urine, and breath.
Metabolic disorders are diagnosed by healthcare providers with the help of screening tests. Blood tests and physical examination are important parts of the diagnosis process. There are many types of inherited disorders and the screening or testing for each disorder is different. Following are some types of diagnostic tools:
Some children may have low glucose problems that may cause lethargy, seizures, or excessive sleepiness. Some children with certain disorders have enlarged spleens or livers. Others may experience changes in their facial appearances that may aid diagnosis. An examination of the inside of the eye may occasionally help narrow down the diagnosis.
The immune system usually protects us against viruses and bacteria. When it senses foreign invaders, it sends out immunological cells to attack them. The immune system can usually tell the difference between foreign cells and their own cells. When you suffer from an autoimmune disease, the immune system mistakes a part of your body such as the skin or joints, as foreign tissues. It releases proteins referred to as antibodies that attack healthy cells. There are more than eighty autoimmune diseases. Following are some of the commonest autoimmune diseases:
The initial symptoms of most autoimmune diseases are very similar and include achy muscles, fatigue, low grade fever, hair loss, trouble concentrating, tingling and numbness in the hands and feet, skin rashes, and swelling and redness. Patients can also have their own unique symptoms. For example, type 1 diabetes results in extreme weight loss, thirst, and fatigue. IBD causes bloating, belly pain, and diarrhoea. When the symptoms increase, it is called flare-up and when the symptoms go away, it is called remission.
A single test cannot diagnose autoimmune diseases. A healthcare provider uses tests, reviews the symptoms you have, and conducts a physical examination so that a diagnosis is established. Doctors usually employ an antinuclear antibody test (ANA) when symptoms indicate an autoimmune disease. A positive test indicates that you might have one of these diseases. It will, however, not confirm which one you have exactly or if you have one for sure.
Other investigations to determine the presence of specific autoantibodies are required. Your healthcare provider might also perform some nonspecific investigations to check for the inflammation these diseases create in the body. A positive ANA blood test may indicate the presence of an autoimmune disease. Your healthcare provider may use your symptoms and the result of other investigations to confirm the diagnosis.
The Immunology Laboratory at Kokilaben Dhirubhai Ambani Hospital, Indore carries out laboratory testing and provides clinical consultation in several broad areas including immunodeficiencies, autoimmune diseases, allergic diseases, and immunoproliferative disorders. They also deal with some aspects of infectious disease serology. A lot of work is carried out together with the Microbiology, Molecular Diagnostics, Virology, and Haematology laboratories that ensure seamless consultations and diagnostic services are delivered for different clinical cases.
For evaluation of immunodeficiency, whether as a result of transplantation or congenital, the laboratory is responsible for testing forming the cusp of the research in the clinical arc. Apart from the services mentioned above, our laboratory provides reference diagnostics for both IgG and IgE related diseases with the help of state-of-the art methodologies.
The Department of Laboratory Medicine at Kokilaben Dhirubhai Ambani Hospital, Indore houses highly qualified and experienced medical professionals who are dedicated to quality service and patient care. Our reports are prepared by highly skilled professionals who pay detailed attention to ensure they are accurate and error-free. Our laboratory follows international protocols and quality standards to help provide precise results. Access the best laboratory in Indore which offers a diverse range of testing facilities with rapid results.
Our team provides high-end services through state-of-the-art infrastructure and follows the highest level of professionalism. Additionally, our staff engages in various training and competency evaluation programmes to be able to deliver precise and accurate results without compromising the quality. Our laboratories are computerised workplaces equipped with high-end software for Hospital Information systems (HIS) on which information regarding the patient’s medical condition and reports is uploaded. This software is accessible to all in-house doctors, thus making patient records accessible just with a few clicks.